ENGINEERING FOR BIOSAFETY
Trainers :
Theodore J. Traum
P.E. Principal World
BioHazTec and CRC Inc.
Barbara Johnson
PhD, RBP Biosafety/Biosecurity Consultant
Outline of course program
Day 1
Basics of Microbiology and Biosafety Practices (BMBP) for High Containment Laboratory Facilities: An overview of BSL 1-3 and ABSL 1-3
The module will provide an overview of biosafety level 1-3 and animal biosafety level 1-3 to include an overview of microbiology, understanding agent risk groups and how they apply to biosafety levels, biosafety practices, and primary and secondary containment strategies. The course materials provided are presentation slide note pages.
Course time is 1 hour
Large Space Decontamination and Sterilization for Facility O&M
This module provides an overview of decontamination and sterilization technologies for room and HEPA filtration units. The course will provide information regarding the relative resistance of microorganisms, techniques employing gas and vapor decontamination and sterilization, and conditions that alter their effectiveness. The course materials provided are presentation slide note pages.
Course time is ½ hour
Codes of Conduct in the Biosciences
The module demonstrates how personalethics are one of the underpinnings of a successful biosafety and biosecurity program. Codes of Conduct act to reinforce ethical norms, raise the awareness of scientists regarding the possible dual use nature of research, and encourage the scientific community. This presentation provides guidelines for the development of an Institutional Code of Conduct that will assist managers, biosafety personnel, and scientists in implementing codes for ethical conduct and measures for governance that are in harmony with ongoing international treaty and legislative activities. The course materials provided are presentation slide note pages.
Course time is ½ hour
Biocontainment Engineering Principles, Part I
This module is designed to introduce engineering principles as a practical approach to biocontainment engineering. Presented are engineering concepts, basic formulas, rules-of-thumb and engineering techniques needed to understand how biocontainment facilities are designed and operate. The impact of Regulations/Guidelines on biocontainment design will be discussed. Engineering and maintenance practices for sustainability of BSL-3 and ABSL-3 will be introduced. Introduction to HVAC building systems and controls for high containment laboratories will be presented. The course will include group classroom exercises. The course materials provided are presentation slide note pages, metric scales and calculators.
Course time is 4 hours
Day 2
Understanding and Assessing Risk
This module is to identify components associated with biologically hazardous materials, identify the information needed to assess and mitigate risk, understand the objective and subjective components of the process, and learn how to better communicate risk. Interactive class exercises are incorporated into the lecture. The course materials provided are presentation slide note pages.
Course time is 1 ½ hours
Biosecurity
The Biosecurity course will provide an overview of biosecurity to include why biosecurity is important, and aspects of facility design and practices. There will be a discussion of threats, vulnerabilities and mitigation strategies as well as roles and responsibilities for laboratory personnel. Interactive class exercises are incorporated into the lecture.
Course time is 1 ½ hours
Biocontainment Engineering Principles, Part II
This is a continuation of Biocontainment Engineering Principles, Part I from Day 1.
Course time is 3 hours
Day 3
Essentials of Facility Design and Construction Techniques
The module is designed to provide the attendees with an insight into the design and construction process for a high containment laboratory. The course begins with a presentation of typical design and construction pitfalls as well as examples of innovative biocontainment design features. Presented will be a process for the successful design and construction of a containment laboratory to ensure that a facility can be designed and constructed within scope, schedule and budget. The course presents the importance of process flow and a checklist approach to assure design elements critical to certification and a safe laboratory environment are addressed. It examines biocontainment design decisions and their impact on energy, operating costs and budget. The course concludes with a group design project. This is a team building exercise which utilizes course material, hands-on experience and personal interaction skills to work with a group of persons from different professional backgrounds to design a containment laboratory. The design parameters, building constraints, research program and various other design parameters will be provided as a case study exercise. Intermittently during the course, time will be provided for the groups to meet and discuss their approach, issues and suggestions for the design solution. With the skill sets developed during the course, attendees will be able to develop schematic hand drawn drawings of the containment laboratories, and hand drawn schematics of mechanical and electrical systems which will be used as part of the group’s presentation. This is a problem solving, team building exercise structured to replicate a real life project in which attendees will most likely participate during their careers. Final group design projects will be presented on Day 5. The course materials provided are presentation slide note pages and group design project material.
Course time is 6 hours
Day 4
Airflow for High Containment Laboratories
The module provides basic principles for the design of HVAC and exhaust systems for high containment laboratories. Concepts and designs of directional airflow of HVAC/exhaust systems, filtration schemes, noise issues, ductwork design and control systems will be presented. Measuring airflow, pressure differentials and smoke testing will be hands-on experience. Failure scenarios for evaluating systems will be presented. Classroom group exercises will be conducted on developing failure scenarios. The course materials provided are presentation slide note pages and a metric ductulator.
Course time is 4 hours
Continue Work on Group Design Projects and Containment Facilities Tours
Groups will continue working on their group design projects. Groups in turn will tour a BSL-3 facility and an ABSL-3 facility. The tours are designed to familiarize the attendees with the information presented in the course for a hands-on experience and provide a stimulus for containment problem solving. The tour experience will assist the attendees in the formulation of their design solutions for the group design project.
Course time is 2 hours
Day 5
Construction and Commissioning of High Containment Laboratories
This module presents creative techniques to ensure successful construction as per the design. The use of a commissioning agent and use of functional performance testing is presented. Inspection and contractor training principles to insure quality are introduced. A group exercise on writing functional performance tests will be conducted. The course materials provided are presentation slide note pages.
Course time is 1 hour
Preparing for Certification of a High Containment Laboratory
The PCHCL course is to prepare biosafety officers, operators and maintenance personnel for mock certifications prior to regulatory and/or third party certification. Safety management, biosafety standard operating procedures and facility validation will be discussed. The course materials provided are presentation slide note pages.
Course time is 1 hour
Troubleshooting and Maintaining High Containment Laboratory Systems
This module will focus on the creation of an operation and maintenance program and plan. Components and building systems will be analyzed to identify planned maintenance and also unplanned maintenance. Maintenance safety concerns and methods to insure quality maintenance systems will be discussed. Attendees will participate in the development of a operating and maintenance plan for a model laboratory. The course materials provided are presentation slide note pages.
Course time is 2 hours
Laboratory Group Design (Projects) Presentations
Based upon course materials, hands-on experiences and personal experiences, each group will have the opportunity to present their solution to the design project assigned on Day 3. A round table discussion will follow each presentation for an exchange of ideas and opinions. This is the culmination of the course which is a demonstration of a team approach to biocontainment, and operations and maintenance problem solving.
Course time is 2 hours
| COURSE FEES |
| Members' rate: S$1200 |
| Standard rate: S$1400 |
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| REGISTRATION |
| Closing date for registration is 15th August 2008. Download registration form here. |
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| For Inquiry |
Please call
Dora (Tel: +65 6872 7072, email: doralam@tll.org.sg) or
Mee Lan (Tel: +65 6872 7071, email: meelan@tll.org.sg).
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Course Co-Ordinator:
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