Biosecurity & Biosafety –  New Challenges of Bio Threat in a Rapidly Changing World of Science & Technology. 12th APBA Biosafety Conference.

Registration

Date:

22 August 2017 - 25 August 2017

Venue:

Lotte Legend Hotel Saigon - Ho Chi Minh City, Vietnam

Registration Fees

Members Rates

Pre-Conference Workshops:
22nd August -  23rd August 2017


Day 1: 22nd August 2017

Workshop 1: Biorisk Assessment – Principle and Methodology (Fullday)

SGD500

Workshop 2: A Preparatory Course for IFBA Professional Certification Examination. Biorisk Management (Fullday)

SGD500

Day 2: 23rd August 2017

Workshop 3: Biocontainment Design and Engineering for Biosecurity (Fullday)

SGD500

Workshop 4: Leadership and Empowerment in Biorisk Management (Halfday AM)

SGD250

Workshop 5: Responding To Biorisk Emergency – Theory & Scenario Table Top Exercise (Halfday PM)

SGD250

Workshop 6: Laboratory Biorisk - Monitoring and Evaluation (Fullday)

SGD500

Conference Registration Fee

SGD950

Networking Dinner (24th August 2017)

SGD60

Rate quoted is applicable per workshop

Total:

Registration Fees

Non-Members Rates

Pre-Conference Workshops:
22nd August -  23rd August


Day 1: 22 August 2017

Workshop 1: Biorisk Assessment – Principle and Methodology (Fullday)

SGD600

Workshop 2: A Preparatory Course for IFBA Professional Certification Examination. Biorisk Management (Fullday)

SGD600

Day 2: 23 August 2017

Workshop 3: Biocontainment Design and Engineering for Biosecurity (Fullday)

SGD600

Workshop 4: Leadership and Empowerment in Biorisk Management (Halfday AM)

SGD300

Workshop 5: Responding To Biorisk Emergency – Theory & Scenario Table Top Exercise (Halfday PM)

SGD300

Workshop 6: Laboratory Biorisk - Monitoring and Evaluation (Fullday)

SGD600

Conference Registration Fee

SGD1050

Networking Dinner (24th August 2017)

SGD60

*Program and speaker is subjected to changes without notice. The event online registration starts from now and ends on 16th August 2017.

Cancellation Policy
All cancellation must be made in writing to the Secretarial. Cancellations received on or before 23rd July 2017 will be refunded in full less an administrative charge of SGD100.00. No refund will be made for cancellation received after 23rd July 2017.

Conference Highlight

 

Biosecurity & Biosafety - New Challenges of Bio Threat in a Rapidly Changing World of Science & Technology

Co-organiser: National Institute of Hygiene and Epidemiology (NIHE), Hanoi, Vietnam

 

2 days Pre-Conference Workshops & 2 days Conference highlights:

  • Bioterrorism in Reality – What You Should Know
  • Leadership in Biorisk Management – The Need for Empowerment
  • Updates from WHO on Laboratory Biosafety Manual 4th Ed.
  • New Challenges of Biothreat in Rapidly Changing World of Science & Technology
  • Livestock, Food, Water & GMOs - Biorisk of Agricultural Concerns & Agro-terrorism 
  • Emergency Response in Biosafety vs Biosecurity – Essentials that You Should Know
  • Biocontainment Facilities – Addressing Biosecurity Issues in Design & Engineering
  • Bio-Preparedness in the Next Pandemic –  Strategy for Natural Occurrence or a Deliberate Release
  • Opportunity for networking - Experience sharing and networking with international biosafety safety experts
  • Opportunity for exhibition & sponsorship - Exhibits showcasing the latest in laboratory biosafety and biosecurity products and services

 

Other conference activities:

  • IFBA Biosafety Professional Certification Course & Examination
  • NSF49 BSC Certification Course for Accreditation of Field Certifiers
  • A-PBA AGM on 24 August 2017

Introduction

This regional conference aims at generating a forum exchange on the various current Biosafety and biosecurity issues of concern at the global, regional, national and technical level.

 

Topics of discussion range from biorisk, bio-preparedness to sharing of scientific knowledge and technical issues of concern in the region. Special features include current hottest debate on Sciences and Technology VS Bio Threat of multidiscipline, updates on new innovative biotechnology, duel use etc.

 

International biosafety experts and professionals from around the world will be speaking and sharing their knowledge and experiences. This conference will be a valuable opportunity for networking and be updated with the current development on biosafety and biosecurity uniquely to the Asia-Pacific region.


Who Should Attend

  • Biosafety Professionals and practitioners
  • Researchers and laboratory workers
  • Biosafety Managers & Consultants
  • Engineers and Architects
  • Suppliers and Vendors
  • Professionals interested in updates of biosafety and biosecurity
  • Senior Administrations, Directors and Managers from healthcare industry, educational institutes, veterinary and other industry cluster

Who Should Sponsor?

Anyone who supplies, manufactures, provides services or products correlated to biomedical research or biological safety.

Call for Oral / Poster Presentation 

 

We are inviting biosafety practitioners and professionals who wish to share their experiences and expertise to submit the abstract for poster presentation at the conference.

 

The A-PBA Organizing Committee invites submission for oral / poster presentation at the 12th A-PBA Annual Conference that will be held from 22nd Aug to 25th Aug 2017 in Ho Chi Minh, Vietnam. The theme of the conference is: "Biosecurity & Biosafety –  New Challenges of Bio Threat in a Rapidly Changing World of Science & Technology"

 

The following broad topics are the focus for the A-PBA Conference however, papers on other appropriate topics that relate to the goals of the conference will be considered

  • Biosafety / Laboratory Biosafety /Biosecurity / Laboratory Biosecurity
  • Regulatory initiatives impacting biosafety and biosecurity
  • Containment facility design, commissioning, maintenance and operation
  • Biorisk applications related to Infectious diseases affecting humans or animals
  • Containment/laboratory equipment
  • Biological risk assessment / mitigations and communication
  • Applied research and innovations impacting biosafety and biosecurity

 

The abstract submission deadline is 30th June 2017. Selected abstracts will be printed in the conference program booklet.

For more information on poster presentation, please contact our A-PBA secretariat at secretariat@a-pba.org or Ms Diah Iskandar 'Diah Iskandriati' atie@indo.net.id


Guidelines for Submission of Abstract for Oral / Poster Presentation

 

Each registrant may submit one abstract of his or her presentation during the conference.

 

Please take note that all abstracts will be reviewed by the scientific committee. They will decide on the final acceptance for either oral or poster presentation for each abstract. All registrants will be advised accordingly by 30th July 2017.

 

Selected abstracts will ONLY be accepted upon receipt of registration and payment for the conference fee.


Abstracts

 

  1. All abstracts must be in ENGLISH, the combined length of the abstract title, list of authors, and body should not exceed 300 words. Please be sure to carefully check your abstract for content errors, spelling, names, etc. before submitting. A-PBA does not proofread for correct spelling, typographical, grammatical, or scientific errors, nor can changes be made once the abstract is submitted.
  2. Title should be brief, in bold capital letters at the top of the abstract.
  3. Author(s) should be listed by surname (underline) and initials, with the presenting author’s name underlined. The designation and organization should immediately follow the authors’ names. (Organization/Institute, department, city, state, country of author).
  4. Text must be typed single-spaced, font 12 Arial with only the left margin justified.
  5. Leave one line between the title/author/institution and the body  of the abstract.
  6. Each abstract should contain: (a) an introductory sentence indicating the objective of the abstract (b) main content, including methods and results if relevant and (c) conclusions. It is expected that the abstract will include the summary of the original presentation.
  7. Graphs, tables and illustration cannot be included in the abstract.
  8. The abstract document MUST BE in WORD.doc format. Any other file type WILL NOT be accepted.
  9. Abstracts must be submitted by email to secretariat@a-pba.org as Microsoft Word attachment.

 

*Note to All Presenters

**The Organizing Committee reserves the right to amend or change any part of the submission guidelines without prior notice.

 

Pre-Conference Program

 

Day 1: Tuesday, 22 August 2017

Time / Workshop No.

Program

Speakers

09.00 - 17.00

WS 1

Room 1

Biorisk Assessment – Principle and Methodology

  • Risk identification and evaluation
  • Risk control and performance assessment
  • Extension of Biorisk assessment to CBRN Preparedness

Ms Chook Mee Lan

Dr Se Thoe Su Yun

 

09.00 - 17.00

WS 2

Room 2

A Preparatory Course for IFBA Professional Certification Examination. Biorisk Management

  • The essential elements of CWA 15793
  • Core competencies of a biosafety professional Internal certification exam: Syllabus Outline & preparation

Prof Lim Yang Mooi

Dr Tan Cheng Siang

 

 

Day 2: Wednesday, 23 August 2017

 

Time / Workshop No.

Program

Speakers

09.00 - 17.00

WS 3

Room 1

Biocontainment Design and Engineering for Biosecurity.

  • Design & Engineering Principles of Biocontainment Facility - concept for both BSL3 & ABSL3
  • Integrating Function, Form & Budget – Get it right the first time
  • Design consideration - Energy saving & sustainability, Commissioning & certification consideration
  • Maintenance Considerations & development of Facility SOP

Dr Antony Della-Porta

Dr Chua Teck Mean

09.00 - 12.00

WS 4

Room 2

Leadership and Empowerment in Biorisk Management

  • Managing Human Factors in Biorisk (Attitudes and behavior )
  • Leadership and Personal Accountability  etc
Dr Jim Welch

14.00 - 17.00

WS 5

Room 2

Responding To Biorisk Emergency – Theory &  Scenario Table Top Exercise

  • First Aid (heart attack, injury, etc)
  • Chemical 
  • Biological
  • Transportation 
Prof Lim Yang Mooi

09.00 - 17.00

WS 6

Room 3

Laboratory Biorisk - Monitoring and Evaluation

  • Developing a National Biorisk Monitoring and Evaluation Framework
  • Laboratory Auditing – Principal and Methodology
  • Table top exercise

Mr David Lam

Mrs T.S. Saraswathy

 

 

Conference Program

 

Biosecurity & Biosafety – New Challenges of Bio Threat in a Rapidly Changing World of Science & Technology

 

Day 1: Thursday, 24 August 2017

Time

Program

Speakers

08.00 – 09.00

Registration

 

Welcome & Opening

09.00 – 09.10

Welcome and Opening Remarks

Dr Chua Teck Mean, President A-PBA

09.10 – 09.20

Opening Address by Guest of Honor

MOH Vietnam

09.20 – 09.35

Culture Dances

 

09.35 - 09.45

Group Photo

 

09.45 – 10.15

Keynote Speaker

Interpol's Bioterrorism Prevent Unit's activity to Strengthen Global Biosecurity

Dr Dennis Adriao

Counter Terrorism Directorate, INTERPOL

10.15 - 10.40

Coffee/Tea Break

 

Session 1

Bioterrorism in Reality – What You Should Know

Chairperson: Dr. Lee Hei Chan

10.40 – 11.00

WHO updates  – revision of the WHO Laboratory Biosafety Manual

Dr Kazunobu Kojima , WHO

11.00 – 11.20

OIE's Biological Threat Reduction Strategy

Dr Christine Uhlenhaut, OIE

11.20 – 11.40

Working Together Makes a Defference - Implementing GHSA and JEE Alliance in Partnership with Biosafety Associations

Mrs Maureen Ellis, IFBA

11.40 – 12.00

The Contribution of The Biological Weapons Convention to Global Biosecurity

Dr Daniel Feakes BWC

12.00 – 13.10

Lunch Break

 

Session 2

Leadership in Biorisk Management – The Need for Empowerment

Chairperson: Dr. Edith Tria

13.10 – 13.30

Biorisk Business: Smart Investments

Ms Amal Haq, BEP USA

13.30 – 13.50

Lessons from 2015 MERS Outbreak in Korea

Prof Nam Taek Lee, Korea University, Korea

13.50 – 14.10

Strategy of Laboratory Biosafety Management in Taiwan

Dr Shu-Hui, Tseng, Taiwan

14.10 – 14.30

Global Health Ethics: Toward Common Principles and their Practical Application to Health Research, Clinical Care and Systems Management

Dr Irene Anne Jillson, Georgetown University

14.30 - 14.50 Current Situation and Plan on Strengthening Biosafety and Biosecurity in Vietnam

Ms Nguyen Minh Hang

General Department of Preventive Medicine, MOH, Vietnam

14.50– 15.10

Coffee/Tea Break

 

Session 3

National Bio-Preparedness in the Next Pandemic

Chairperson: Dr. Nguyen Thanh Thuy

15.10 – 15.30

Identifying Critical Points in Biosecurity Management towards Biopreparedness

Dr Joy P Calayo, PhBBA, Philippines

15.30 – 15.50

Capacity building in biorisk management in Southeast Asia – EU CBRN CoE46

Dr Philippe Stroot, Xibios, Belgium

15.50– 16.10

National Preparedness - Harnessing Science Over Fear of Biological Threat

Dr Asadulghani, Bangladesh

16.10 – 16.30

Role of CBRN in National Bio-Preparedness

Dr Harro Wittermans

UNICRI - United Nations

16.30 – 16.50

Strengthening Capacity Building of Global Health Security in Considering Threats of Biologival Agents in Indonesia

Col. Dr Yuli Subiakto, Indonesia

16.50 – 18.00

18.00 – 18.45

A-PBA AGM
Meeting of A-PBA, IFBA, PhBBA and all National Biosafety Associations/Working Groups in the Asia-Pacific

 

Day 2: Thursday, 25 August 2017

Time  

Program

Speakers

Session 4

Challenges of Biothreat in Rapid Changing World of Science & Technology

Chairperson: Dr. Lim Yang Mooi

09.00 – 09.20

Biorisk Challenges in Synthetic Biology that Every Scientist Should know

Dr Piers Millet, IGEM

09.20 – 09.40

Biosecurity Challenges for Biosafety Practitioners

Mr David Lam

09.40 – 10.00

Staphyphage : Biorisk Reduction in Mrsa Reseach

Dr Tan Cheng Siang

10.00 – 10.20

Impact of Technology on Biosecurity and Biosafety - Transportation of Hazardous sample

Dr Pharm Quang Thai Epidemiology Dept NIHE

10.20 – 10.50

Coffee / Tea Break

Session 5

Ethics, Sciences & Biorisk

Chairperson: Dr. Hsing Ming Chen

10.50 – 11.10

Essential Leadership in Bioethics

Dr Jim Welch

11.10 – 11.30

Human Factors and System Safety how does it translate to real life?

Dr Viji Vijayan

11.30 – 11.50

Confronting the Dual Use Dilemma and the International Network on Biotechnology

Prof Irma Macalinao

11.50 – 12.10

Bioethics, Biosafety and Biosecurity Issues in Stem Cell Research

Mrs T.S. Saraswathy

12.10 – 13.30

Lunch Break

 

Session 6

Laboratory Biorisk in Asia Pacific

Chairperson: Dr. Ni Ketut Susilarini

13.30 – 13.50

Biocontainment Facilities – Addressing Biosecurity Issues in Design & Engineering

Dr Antony Dela-Porta, Bio2ic

13.50 – 14.10

Biosafety Level 3 Facility : Biosafety Versus Operation Cost

Dr Nguyen Thanh Thuy, NIHE Vietnam

14.10 – 14.30

Ways Forward for Biosafety and Biosecurity Program in Cambodia

Dr Sau Sokunna, Cambodia

14.30 – 14.50

Biosafety Practice and Training in Western Africa during the 2014 - 2016 Ebola epidemic : supports from China CDC

Dr William J. Liu, CDC, China

14.50– 15.10

Laboratory Biorisk and Beyond – Challenges of Developing Countries

Dr Darouny Phoneko, Laos

15.10– 15.40

Coffee / Tea Break

Session 7

Livestock, Food, Water & GMOs - Biorisk of Agricultural Concerns & Agro-terrorism

Chairperson: Dr. Asadulgani

15.40 – 16.00

NSF Accreditation of Biosafety Cabinet Field Certifiers

Ms Maren Roush, NSF International, USA

16.00 – 16.20

CRISPR-Cas9: Promises and Challenges

Prof Lim Yang Mooi, Universiti Tunku Abdul Rahman, Malaysia

16.20– 16.40

German - Sudanese Partnership Program for Excellence in Biological and Health Security Strengthening Biosafety & Biosecurity

Dr Adil Ismil

16.40 – 17.00

Closing Remark A-PBA President

 

Note: Program and speakers will be subjected to change without notice

 

 

Speaker Abstract

 

 

Dr. Su Thoe Su Yun

 

Ms. Chook Mee Lan

 

PERFORMING BIOLOGICAL RISK ASSESMENT- Principle and methodology

Dr Se Thoe Su Yun. Deputy Director, Biosafety Branch, Singapore Ministry of Heath.

Ms Chook Mee Lan.  Assistant Director, Facilities Services & Safety.  Temasek Life Sciences Laboratory, Singapore.
 

This workshop introduces the principles of performing risk assessment in a biological environment. The methodology used is Activity Base risk assessment which includes hazard identification, evaluation, risk control and performance assessment. There will be class exercise with practical examples. Participants would be able to perform risk assessment in a systematic manner from technical measure, action to documentation by end of the workshop. There will also be a lecture touching on extension of Biorisk assessment to CBRN Preparedness


Dr. Tan Cheng Siang

Prof. Lim Yang Mooi

A Preparatory Course for IFBA Professional Certification

Examination: Biorisk Management

Dr. Tan Cheng Siang1 and Prof. Lim Yang Mooi2*

1Centre for Tropical and Emerging Diseases, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak,

94300 Kota Samarahan, Sarawak, Malaysia.

2Department of Pre-Clinical Sciences, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Lot PT21144, Jalan Sungai Long, Bandar Sungai Long, 43000 Kajang, Selangor Darul Ehsan, Malaysia

 

The International Federation of Biosafety Associations (IFBA) offers professional certification in biorisk management for biosafety professionals worldwide. This professional certification not only could enhance the credentials of certificants, it is also very vital for career advancement and essential for recognition among colleagues and employers. In view of the importance of professional certification in biorisk management, Asia Pacific Biosafety Association (APBA) in collaboration with IFBA organise a preparatory course for IFBA professional certification examination for biosafety professional from this region. The course covers the fundamental topics that include Fundamental of Biorisk Management, CWA 15793 Laboratory Biorisk Management, Implementing a Biorisk Management System and Roles and Responsibilities for Biorisk Management.  Case studies is integrated in this course to enhance effective learning among participants. Upon the completion of the course, participants would acquire the body of knowledge in biorisk management. Through this professional certification, more certificants with high standard of excellence and technical competency will be engaged to implement biorisk management system in this region.

 

Responding To Biorisk Emergency: Theory & Scenario Table Top Exercise

Prof. Lim Yang Mooi

Department of Pre-Clinical Sciences, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Lot PT21144, Jalan Sungai Long, Bandar Sungai Long, 43000 Kajang, Selangor Darul Ehsan, Malaysia

 

The global efforts through various agencies have created awareness in implementing biorisk management system to strengthen safe conduct in research laboratories. This is critical to provide a safer working environment with maximum protection to human, plant, animal, community and environment. Through these efforts, many people are more aware of the matters pertaining to laboratory bisosafety and biosecurity, and also concern about public health emergency, such as a natural disaster, act of terrorism or disease outbreak. Nevertheless, many are still not aware of the importance of emergency preparedness and response. Emergency preparedness and response is another area that should receive the same level of attention, as well as the resources and plans in anticipating such emergency should be in placed for any possible emergencies. This course introduces the concept of emergency and incident response, as well as to provide a framework on how to respond to any emergencies and incidents. In addition, interactive session on responding to emergency and incident will be focused on first aid, chemical and biological spillage, as well as transportation.  At the end of the course, participants would gain the ability to recognize and respond to the emergency and incident happen in their laboratory appropriately.

 

CRISPR-Cas9: Promises and Challenges

Prof. Lim Yang Mooi

 

The discovery of double helix DNA in 1950s has lead to tremendous achievement and advancement in the field of biochemistry and molecular biology. Subsequently, the development of recombinant DNA technology in 1970s has changed the paradigm in biological research, where more novel biotechnological tools have been developed, and this enable scientists to make more research breakthrough to provide solutions for major medical problems. The recent discovery in genome editing technology (CRISPR-Cas9) has marked another huge milestone in molecular biology research, where scientists could genetically engineer organism to the desire functions. CRISPR-Cas9 is the emerging genome editing technology that allows direct editing on DNA sequence and modulates the function of the DNA sequences in the endogenous context of cells. This report discusses the development and the potential applications of CRISPR-Cas9 in biological research, biotechnology and medicine. This is a remarkable advancement in science that benefits humankind. Contradictorily, this powerful and versatile tool can be potentially applied in none academic arena and pose risk to humankind. Thus, CRISPR-Cas9 has been added in the list of dual-use research concern, where effort is required to prevent this tool to get beyond regulation.


Dr. Tony Della-Porta

 

Dr. Chua Teck Mean

Biocontainment Design and Engineering for Biosecurity

Dr. Tony Della-Porta

Managing Director

Biosecurity and Biocontainment International Consultants (Bio2ic), Sydney, Australia

Dr.Teck-Mean Chua

Biosafety Consultant

Temasek Life Sciences Laboratory, Singapore

 

This workshop will cover the details of BSL-1, BSL-2, BSL-3 and BSL-4 laboratories and physical security measures for these laboratories.  The old style BSL-2 laboratories that form the backbone for medical and veterinary diagnostic work have undergone a significant change over the last few decades moving away from small individual purpose specific laboratories to larger multifunctional laboratories which have increasing flexibility built into them to allow for modern changers in work such as provided increasingly by robotics. The process of consultation, risk assessment and work flow analysis to produce laboratories that are suitable for the users is described.  This is associated with a consideration of design principles such as site factors, standards and regulations, a first look at budgeting and construction principles.  Finally we shall cover the types of equipment found in laboratories and the move to robotics.

 

Biocontainment facilities – Addressing biosecurity and biocontainment issues in design and engineering

Dr Tony Della-Porta

 

Most biocontainment facilities are biosafety level 2 (BSL-2) facilities in which most human, animal and plant pathogens are handled.  These pathogens present a low personal and environmental risk.  They still represent a risk of infection to the general public who should not be permitted to access BSL-2 laboratories.  The biosecurity and biocontainment requirements will be briefly described.  Higher risk agents are handled in BSL-3 and BSL-4 laboratories and the cost and engineering requirements are significantly higher for these laboratories than for BSL-2 laboratories  BSL-3 facilities are required for Risk Group 3 pathogens which pose a significant risk to personnel and to the environment.  BSL-4 facilities are for Risk Group 4 agents that pose an extreme risk for the staff and the environment.  The requirements for BSL-3 and BSL-4 facilities will be described, together in modern trends for design and construction of BSL-2 to BSL-4 facilities.


 

Essential Leadership in Bioethics

Dr. Jim Welch

Executive Director

Elizabeth R Griffin Foundation

 

The sciences of health are about improving the everyday lives of humans, animals and the natural resources that sustain us all. We are about working to prevent, detect and respond to outbreaks that can threaten villages, nations, regions and the world. In that mission, we must often confront situations where risks are uncertain, approaches and methodologies are unique and the potential for misuse by intent or accident can be catastrophic. The requirement that we do that as institutions places us in the category of ‘high reliability organizations.” To maintain high reliability, it is a prerequisite that we commit to an unquestionable path of maintaining public trust in our work. That commitment requires everyone involved to be a leader in the ethics of our work.


 

 

Mrs T.S. Saraswathy Subramaniam

 

Mr David Lam

Laboratory Biorisk - Monitoring and Evaluation

Mrs T.S.Saraswathy Subramaniam

Malaysia

Mr. David Lam

Assistnat Director, Biological Safety

Singapore General Hospital

 

Laboratory AUDIT

Course Synopsis

Auditing, the systematic evaluation of an organization, is inevitable at recent days. The purpose of an audit is to document whether an organization complies with all necessary requirements specified in the audit standard and applicable legislations. The purpose of safety in workplaces is to eliminate risks, implement adequate control measures to eliminate or reduce occupations safety risks to employees, visitors and other stakeholders. Safety audits will help the organization to get an independent view on various safety initiatives implemented and also provide a record of their due diligence on safety implementation. There are different approaches to a safety audit. This course shares with the participants some of the elements in laboratory audits.

 

Bioethics, biosafety and biosecurity issues in stem cell research

Mrs T.S.Saraswathy Subramaniam

Malaysia

 

Stem cells are a class of undifferentiated cells that are able to differentiate into specialized cell types. There are two types of stem cells which have the potential to be used in stem cell-based therapies: multipotent adult stem cells  and pluripotent  stem cells that include embryonic stem cells and induced pluripotent stem cells.

Research using human stem cell preparations holds promise for an increased understanding of the the early stages of genetic diseases, including cancer, and in future applications in cell transplantation therapies for human diseases.  There is now an explosion of R & D research, worldwide using stem cells. This rapidly advancing field has shown many gaps in our knowledge and understanding of stem cell technologies and applications. Many countries have established policies and guidelines that govern research involving stem cells to ensure that such research is conducted in an ethically responsible  manner. Although these policies govern bioethical issues, they are inadequate to address laboratory biosafety.  Current approaches to biohazarad risk assessments and mitigation are more  relevant for microbiological hazards and less appropriate for cell derived materials. Hazard characterisation for stem cells will vary depending on stem cell source, origin, type of cell and activities. Hazard identification and characterization will need to consider tumorigenesis of cells as well as risk of adventitious agents for example, blood borne pathogen risk, Mycoplasma and latent viruses which need biorisk management.

Stem cell banking through long-term storage of different stem cell platforms represents a fundamental source to preserve original features of stem cells for patient-specific clinical applications. Many institutions having biobanks storing stem cells from patients need biosecurity awareness to secure these valuable biological materials.

This presentation will address bioethics, biosafety and biosecurity issues in stem cell research.

 

Biosecurity Challenges for Biosafety Practitioners

Mr. David Lam

Singapore General Hospital

 

Development of life sciences has progressed tremendously over the last decade or so. As technology moves forward, they often associate with a “double‐edged sword” effect. When the technology is being applied according to its original intend, we reap its benefits. However, when the application deviates from original intend there is a potential breach in safety envelope. We will take a look at some of the biosecurity challenges that biosafety practitioners may face today


WHO updates - revision of the WHO Laboratory Biosafety Manual

Dr Kazunobu Kojima

Scientist

World Health Organization (WHO)

 

The WHO Laboratory Biosafety Manual has been serving the global biomedical science community for more than three.  Since the release of the present third edition in 2004, there has been remarkable development in life sciences as well as in biosafety, leading to expectation for the revision to fully update its contents and concepts.

In view of the diverse global readership of this Manual, it is proposed to provide core requirements and some further suggestions for additional safety and security measures based upon local risk assessment.  It is also planned to publish monograph or subject-specific booklets as well as to develop training modules in line with the prime concept of the revised Manual.

The proposed revision concepts – typically outlined as an evidence- and risk-based approach – are truly universal, where one can optimise the combination and extent of safety measures based upon local risk assessment, precisely proportionate to the assessed risks.  While the role of Risk Group (RG; aka Hazard Group) in the particular context of national regulatory framework is noted, our proposition is to dissociate equation of RG of pathogens and biosafety level (BSL) with a thought that the level of risk substantially varies according to elements such as procedures (e.g. propagative or non-propagative), volume/titre etc.  Also each RG consists of pathogens that pose various transmission routes, requiring different control measures.  This novel approach and a particular emphasis on good microbiological practice/procedures would help attain much desired equitable access to diagnostic services without necessitating technically and financially highly challenging containment facilities (e.g. BSL-3) in resource-limited countries without compromising safety.  This is one of the lessons that we’ve learnt from the recent devastating Ebola outbreak.

This presentation is intended to share the key revision concepts and update and to gather thoughts and suggestions as part of a broad consultation process.


 

OIE’s Biological Threat Reduction Strategy

Dr. Christine Uhlenhaut

Chargée de mission for Biological Threat Reduction

World Organization for Animal Health

 

The World Organisation for Animal Health (OIE) is the intergovernmental organisation responsible for improving animal health worldwide. In 2015 the OIE published the current Biological Threat Reduction Strategy which is supported by the OIE’s Sixth Strategic Plan (2016-2020) and cuts across all of its six objectives, namely international communication of global animal disease and zoonosis situation; development and implementation of science-based standards and guidelines on prevention, control and eradication of animal diseases, including zoonoses, and safety of international trade of animals and animal products as well as laboratory excellence; ensuring the scientific excellence of information and advice; capacity-building for national Veterinary Services, including their surveillance and response capacities; and strengthening the organisation’s influence on policy design, applied research and governance.


Working Together Makes a Difference – Implementing GHSA and JEE Alliance in Partnership with Biosafety Associations

Mrs. Maureen Ellis

Executive Director

International Federation of Biosafety Associations

 

Recognizing the need for collective action in building global health security, the International Federation of Biosafety Associations (IFBA) is engaged in ongoing efforts to enhance multisectoral collaboration and foster partnerships between its Member Biosafety Associations and government ministries in the development and implementation of national biosafety and biosecurity action plans. To this end, the IFBA has established membership in both the Global Health Security Agenda (GHSA) Action Package Prevent 3 (APP3) Working Group and the Joint External Evaluation (JEE) Alliance. GHSA planning activities under APP3 recommend that countries develop a strategic plan, informed by a policy framework and including best practices and model national programs, to guide the development and implementation of a national whole-of-government oversight program for pathogen biosafety and biosecurity. The JEE Alliance has been established to give political, financial and technical support to WHO and countries in the coordination and implementation of the country evaluations for compliance to the GHSA and International Health Regulations as well as the ensuing process of capacity building. The main purpose of the Alliance is to serve as a platform for discussion and exchange of views and experiences among partners to facilitate engagement between countries and other relevant organizations and stakeholders involved in health security.

In collaboration with our 39 Member regional and national Biosafety Associations worldwide, the IFBA is engaged in ongoing efforts to implement the GHSA goals under APP3 and the IHR biosafety capacity requirements. Support is provided for developing national biosafety and biosecurity strategies and guidelines, advancing biorisk management practices & procedures, and the certification of competency in biosafety professionals in a variety of technical disciplines related to the safe and secure handling of infectious disease agents. Ensuring that individuals who handle biological materials have demonstrated competencies is an essential component of the overall effort to reduce biosafety and biosecurity risks. 


THE CONTRIBUTION OF THE BIOLOGICAL WEAPONS CONVENTION TO GLOBAL BIOSECURITY

Mr. Daniel Feakes

Chief, BWC Implementation Support Unit

United Nations Office for Disarmament Affairs

 

The 1972 Biological Weapons Convention (BWC) enshrines the strong international norm against the deliberate use of disease as a weapon into international law. Almost 180 States have joined the Convention and therefore ruled out the option of developing, producing or acquiring biological weapons. No State today publicly admits to the possession of biological weapons, or argues that such weapons are legitimate instruments of national security. The BWC therefore makes a strong normative contribution to global biosecurity. This presentation will describe how the BWC also makes a practical contribution to global biosecurity through its legal provisions dealing with, for example, national implementation, preparedness and response, international cooperation and science and technology, and also through assistance programmes for developing countries aimed at improving their capacity to fully implement the BWC and to promote the peaceful uses of biology. In implementing such activities, the small BWC Implementation Support Unit based in Geneva works with relevant international organizations such as the FAO, Interpol, OIE and WHO, and with initiatives such as the Global Health Security Agenda and the Global Partnership. In reviewing relevant developments in science and technology, the BWC also interacts closely with scientists, academics and industry with regard to technical, legal, ethical and regulatory issues. While primarily a security treaty, the BWC also contributes to achieving the Sustainable Development Goals, particularly those relating to peace and justice and to good health and well-being.


Biorisk Business: Smart Investments

Ms Amal Haq

Program Adviser

U.S. Department of State

 

A brief talk that will make a case for institutional investment in implementation of a Biorisk Management System


Lessons from 2015 MERS Outbreak in Korea

Prof. Lee, Nam Taek

Deputy Director of BioDefense Research Institute of Korea University

College of Life and Sciences and Biotechnology, Korea University

 

Nowadays the possibility of bio-incidents is increasing rapidly than ever before, due to frequent emergence of pandemic disease along with intentional bioattacks and accidental release of highly infectious pathogens from laboratories.

The 2015 Middle East Respiratory Syndrome (MERS) outbreak was the largest pandemic which Korean people have ever experienced during the last decade, in terms of economic depression and social panic.

2015 MERS was initially flowed in from Middle East Country by a Korean traveler, and caused 36 death toll out of 186 confirmed cases in three months.

As had been reported before, the characteristics of 2015 MERS-CoV in Korea was nosocomial, which involved not only intra-hospital but also hospital-to-hospital transmission. Based on the epicurve of Richards model, the basic reproduction number was estimated at 11.5 (R0=11.5). This indicates that infection rate of 2015 MERS was uniquely high compared to any other recent pandemics such as New Flu and SARS. The reasons why 2015 MERS outbreak in Korea has shown such a high infection rate will be mentioned in this conference.

In conclusion, the initial stage of biorisk management of 2015 MERS in Korea was rather unsuccessful due to following reasons: lack of knowledge and experience of the physicians about the characteristics of MERS-CoV., delayed confirmation of the first index case, poor sharing of medical information, poor application quarantine criteria, and limited early use of in vitro diagnosis kit.

However, within a three month from the first confirmation, Korean Government with strong will and control tower could finally subdue the spreading of MERS-CoV through struggling efforts, such as chasing the close-contact with the confirmed case and isolation thereafter, increment of the number of negative pressure room, designation of hospitals specialized for MERS treatment, disseminate masks to the public with large scale, active public health education, and etc.

We Koreans had to pay the fiddler to the last MERS attack. However altogether, we had gained priceless lessons from its attack, with which we can effectively counter another round attacks of pandemics in the future.


 

Strategy of Laboratory Biosafety Management in Taiwan

Dr. Shu-Hui, Tseng

Director of Infection Control and Biosafety

Centers for Disease Control, R.O.C.(Taiwan)

 

Since the accident of laboratory acquired infections with SARS-CoV in 2003, Taiwan has acknowledged the importance of laboratory biosafety management. Taiwan CDC referred to other developed countries’ experiences, and by following World Health Assembly resolution 58.29, "Enhancement of Laboratory Biosafety", and referring to the requirements of "Laboratory Biosafety and Biosecurity" in the International Health Regulations (IHR(2005)), we established regulations of laboratory biosafety management. In 2015, to improve the capability of laboratory self-management, we observed the WHO's document "Laboratory Biorisk Management Strategic Framework for Action 2012-2016" and guided BSL-3 and above laboratories to implement the Laboratory Biorisk Management Standard CWA 15793, and then gradually promoted it to BSL-2 laboratories. In 2016, we used the WHO's Joint External Evaluation Tool (JEE Tool) to evaluate our epidemic prevention system (including areas of biosafety and biosecurity) for improving the capability of select agents management.


"Global Health Ethics:  Toward Common Principles and their Practical Application to Health Research, Clinical Care, and Systems Management."

Prof. Irene Anne Jillson

Associate Professor

Georgetown University

 

This presentation will address the discourse related to the relatively disparate efforts to devise a set of common principles for global health ethics.  The presentation will include a discussion of the diverse spiritual bases for bioethics, as well as the recent and current discourse that reflects broad cultural and contextual considerations of this complex and value-laden field.  We will then consider the impetus and pro- and contra- arguments for developing a set of common global health ethics principles.   Finally, we will address the practical ways that such a set of principles could be applied to health research – increasingly multinational; to clinical care – in light of e-health; and to health systems management – given both the expanding role of multinational health corporations and the impact of donors on health systems management of developing countries.


 

CURRENT SITUATION AND PLAN ON STRENGTHENING BIOSAFETY AND BIOSECURITY IN VIETNAM

Ms. Nguyen Minh Hang

Deputy Director

General Department of Preventive Medicine

 

Viet Nam has made important progress in biosafety, as part of a broader plan for strengthening national capacity in public health laboratories.  Progress has been made in developing a biosafety legislative framework and biosafety training capacity in the regional institutes that would enable delivery of training to staff from provincial and district laboratories. Up to now, Viet Nam has 03 Biosafety level III (BSL-III) in 02 regional Institutes (National Institue on Hyginene and Epidemiololy, Pasteur Institute in Ho Chi Minh and Tropical Hospital in Ho Chi Minh city and BSL II in provincial levels. However, biosafety in Viet Nam would be further strengthened by reviewing biosafety legislation and regulations against the international standards, and investment in maintenance and certification of key biosafety equipment such as biosafety cabinets in all Biosafety level 2 (BSL-2) laboratories, training for laboratory staffs on biosafety and building 03 other BSL III in other regions of Viet Nam. In addition, Biosecurity is important in order to secure infectious agents against those who would deliberately misuse them to harm people, animals, plants, or the environment though biosecurity is still a new concept in Viet Nam.

The presentation focus on detailed current situation and plan on strengthening biosafety and biosecurity in Viet Nam, which provide basic information about advantages, disadvantages and lessons learned to develop biosafety and biosecurity system in Viet Nam.


 

Identifying Critical Points in Biosecurity Management towards Biopreparedness

Prof. Joy Potenciano-Calayo, RMT, MSc., CBO

President, Philippine Biosafety and Biosecurity Association (PhBBA)

 

Bio-preparedness is the life-saving core of a biorisk management programme. An effective programme assures the clear distinction between biosafety and biosecurity, and providing a complete, robust and continual improvement of the AMP (Assessment-Mitigation-Performance measurement and improvement) for each.

Biosecurity, though practically instituted at various levels, still warrants more scrutiny. Critical control points are needed in order to optimize its implementation. A considerable amount of unpredictability in science and technology, disease trends in human and animal strongly indicate more stringent measures to minimize, if not eliminate biosecurity risks in concerned laboratories and facilities. This talk shall highlight biosecurity awareness, drive and commitment towards biopreparedness as a local experience. 


Capacity building in biorisk management in Southeast Asia –
EU CBRN CoE Project 46

Dr. Philippe STROOT

Xibios – EU CBRN CoE 46

 

EU CBRN CoE Project 46 aims at the “Enhancement of CBRN capacities of South East Asia in addressing CBRN risk mitigation concerning CBRN first response, biosafety and biosecurity, awareness raising and legal framework”. It involves 8 Southeast Asian countries through the regional CBRN Centre of Excellence located in Manila and their respective National Focal Points. This specific project is a 3-year project that started in September 2015.

Among the 3 components of the project, Component 2 is devoted to biorisk management. It consists of several work packages.  The main one (WP3) is a train the trainer program delivered in two educational pathways. The first pathway aims at training a team of biosafety experts (two per country) in advanced biosafety management (Phase 1), and supporting them to provide a first national training on topics and issues identified by the National Focal Point as important for their country (Phase 2). Phase 1 was ensured through two intensive and highly interactive one-week workshops, held in Vientiane, Laos, and Yangon, Myanmar, respectively, and Phase 2 is starting right after the APBA conference. The second pathway is the training of a number of selected architects and engineers (a maximum of 5 per country) on the design and construction of biocontainment facilities. Two one-week workshops were also conducted in phase 1, one in Manila, the Philippines, the other one in Hanoi, Vietnam. Phase 2 is a short thematic workshop planned for November 2017. Both pathways are driven by strong considerations of sustainability and development of local capacities. A number of experts from SEA were involved as facilitators in both parts of the project, together with European and other experts.

Other parts of Component 2 are devoted to the capacity assessment (WP4) and management of biological waste (WP5). Missions are being conducted in each participating country in order to assess the capacities, vulnerabilities and risks related to diagnostic and research activities in general and to waste management in particular, in view of drafting recommendations and guidelines for national application.

The proposed lecture will focus on the specificities of this project and some of the challenges of such a capacity building program.


National Preparedness – Harnessing Science Over Fear of Biological Threat

Dr. Asadulghani

Head of Biosafety and BSL3 Laboratory & Head (Acting) of Laboratories Operation Management

International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)

 

Biorisk management is the science of conquering our fears and leading courageous acts in the field of microbiological and biomedical research and diagnosis. Human exposure to biological hazards may cause serious consequence that is the interest to the scientists and the public at large. Scientific knowledge is crucial to the competence and credibility of regulations designed to protect public health from biological hazards. Bangladesh is a country in southern Asia, in the Ganges River delta, on the Bay of Bengal. The country is hit by cyclones every year and coastal areas inundated by a storm surge. Emerging and re-emerging pathogens, such as Bacillus anthracis, Nipah virus, highly pathogenic avian influenza virus H5N1, antimicrobial resistant super bacteria, and MDR/XDR- Mycobacterium tuberculosis have been identified as major public health threats in Bangladesh. Current life science infrastructures in the country need significant improvement to address biological threats and promotion of efficient and sustainable culture of biosafety and biosecurity. A multipronged activity has been initiated to strengthen biosafety and biosecurity status in Bangladesh using the platform of Bangladesh Biosafety and Biosecurity Association supported by CDC and BEP, USA. Resource persons have been trained to provide assistance to labs throughout the country in the area of improving biosafety and biosecurity status. Top level, mid level, and bench workers in all divisions of Bangladesh have been sensitized and trained. For robust dissemination of the knowledge and sciences of Biosafety and Biosecurity, the existing webpage was further developed. Guidelines on handling and disposal of biohazardous materials were drafted. All together this suite of activities will help build a sustainable culture of biosafety and biosecurity that will continue to spread within Bangladesh laboratories. The ultimate goal of this initiative is a sustainable development that meets the needs of the present without compromising the ability of future generations to meet their own needs.


STRENGTHENING CAPACITY BUILDING OF GLOBAL HEALTH SECURITY IN CONSIDERING THREATS OF BIOLOGICAL AGENTS IN INDONESIA

COLONEL DR. YULI SUBIAKTO,APT,MSI

Head Subdirectorate of Health Strenght

Directorate of Health Directorate General of Defense Strenght MoD RI

 

Introduction

Indonesia is an archipelagic country with a number of islands more than 17,504   with a very strategic position because it is flanked by two continents and two oceans and is in the path of international trade traffic and traffic peoples.   As a tropical country, Indonesia has a wealth of flora and fauna as a natural resource (biodiversity), partly a microorganism that is useful for health, and at the same time a threat to public health.   As scattered biological resources can become disease agents that cause extraordinary events, even causes of outbreaks exploited from the actions of bioterrorism, biological weapons, biocrime and agretororism.

 

Infectious Diseases of Indonesia

In line with the development of world trade and movement people beginning in the middle ages, some potential contagious infectious diseases that commonly spread in continental Europe, Africa and America and Asian mainland spread to Indonesia such as pes, cholera, dengue hemorrhagic fever, hepatitis, thypus and dysentery. Population dynamics, social culture and environmental changes are also changes in the spread of infectious diseases, including potential outbreaks of infectious diseases. In addition to the increasingly advanced health technology, it is possible to do genetic engineering "Genetic Modified Organism" from disease agents for specific purposes such as bioterrorism, biological weapons, biocrime, agroterorrism to threat human, plant, and animal health.

 

National Defense

The defense of the state of Indonesia is all the defense of the universe, whose organization is built on awareness of the rights and duties of all citizens and the belief in their own power to maintain the survival of an independent and sovereign nation and state of Indonesia.    Observing the development and pattern of diseases caused by various aspects above, Indonesia must make efforts to prevent, control, combat and combat infectious diseases, both endemic and spread from other countries.    Indonesia as a member country of the United Nations has agreed to implement the provisions of International Health Regulations (IHR) 2005 and is required to have the ability in the prevention, early detection and rapid response to the emerging and re-emerging diseases or events that potentially cause public health emergencies that disturb the world PHEIC.  Global Health Security as a means to strengthen the capacity to prevent, detect and respond to infectious diseases, pandemics and bioterrorism, biological weapons, biocrime and agroterorism through the implementation of International Health Regulation (IHR) 2005 more effectively.   Strengthening capacity building of human resources, infrastructure and facilties, software, code of conduct, biorisk management are needed global health security considering threat of biologigal agent use to realize National Defense strong.

 

Conclusion

The threat of state defense derived from biological agents is expressed as a real threat because it has the potential to cause an epidemic that could threaten the health of plants, animals and humans, which can cause economic harm, human health and disrupt the security of the country. So that required comprehensive countermeasures ranging from preventive, detection and emergency measures with the step of strengthening capacity building of Global Health Security on human resources, infrastructure and facilty, software, code of conduct, biorisk management.


BIORISK CHALLENGES IN SYNTHETIC BIOLOGY
THAT EVERY SCIENTIST SHOULD KNOW

Dr. Piers MILLETT

Director of Safety and Security

iGEM

 

As an international synthetic biology competition, iGEM is a microcosm of the safety and security challenges facing the field. The parts-based nature of synthetic biology challenges oversight frameworks based upon the origin of parts, rather than their function in context. The international nature of the competition requires us to operate across different legislative and regulatory frameworks. The technologies chosen by our teams often sit on the cutting edge of what is possible, often in advance of national or international policies to govern them. By embedding projects in real-world problems, our projects are governed by a wide range of regulators, often run by different agencies, with their own rules, processes and cultures. The interdisciplinary nature of the enterprise necessitates engagement across a wide range of communities on efforts to keep the field safe and secure.

This presentation explains the procedures and practices that iGEM uses to overcome these challenges, including how it screens the projects and parts used in the competition. A series of case studies -- from context-specific risk assessment, through oversight of gene drives, to animal use -- showcase how our safety and security policies are derived from, and help to address, real-world practical challenges. We also highlight how iGEM is an innovator of, and a test-bed for, new safety and security practices better adapted for engineering biology.


 

Bio-safety in sample collection and transportation from investigation site to laboratory. From theory to practice

Dr. Pham Quang Thai

Vice Head of Epidemiology Department

National Institute of Hygience and Epidemiology

 

Background: The rapid development of Viet Nam, with increasing urbanization, increasing animal production, changes in dietary habits and other social behaviors, and increasing inequalities of income will deliver new infectious disease challenges over the coming years. Furthermore, Vietnam stay in Southeast Asia which is a hot spot with 42% of the world emerging infectious diseases. The scale, speed and complexity of emerging and re-emerging infectious diseases are overwhelming capacity to comprehend and cope. The readiness of the system for disease investigation require both lab and epi people to understand and cooperate with each other to know what when and how to do the investigation, collect sample as well as transport sample from site to lab.

Materials and Methods: We developed the national integrated ‘Epi/Lab’ toolkit for training the staffs of laboratory and epidemiology on early detection and rapid response to emerging and re-emerging infectious diseases which very necessary and useful to improve the capacity of our Preventive Medicine System on communicable disease surveillance and control. Several training workshop were conducted for all 4 regions in Vietnam on epi-lab integration so that lap person can understand epidemiology work and epi person can understand basic lap technique that finally strengthening the collaboration between epidemiology and laboratory in outbreak surveillance, investigation and response.

Results: Laboratory and Epidemiology staffs from regional institutes and selected Preventive Medicine Centers of Northern, Central, Highland, Southern parts of Country join the training and contribute to the toolkit. Both epi and lab person share experience from field investigation on how to collect samples and how to send samples to lab safety. SOP for sample collection and epi-investigation were finalized that suit both epi and lab to help them understand better to cooperate in field work.

Conclusion: the final toolkit for epi-lab integration can help both epi and lab people understand the work and help them corporate with each other that finally improve the safety of sample collection and transfer as well as better disease investigation.

Key Words:  bio safety, epi-lab integration.


 

HUMAN FACTORS AND SYSTEM SAFETY HOW DOES IT TRANSLATE TO REAL LIFE

Dr. Viji Vijayan

Assistant Dean, Safety, Health and Emergency Management

Duke-NUS Medical School

 

Exactly what is meant by human factors and systems safety, and how does it translate into real life? Humans live and work within a socio-technical system consisting of humans, machines, processes, regulations, organizational structure, environmental conditions, and many other factors. How we interact with the different components of this socio-technical system constitutes human factors and/or ergonomics. In order to be efficient (productive) the human has to interact with the various components in a particular way; in order to assure quality (safety) the human may have to change the way in which he or she interacts with the components. What is the right balance to achieve both efficiency and safety? There are constant goal conflicts in life and we make tradeoffs all the time. This is the “Efficiency–Thoroughness Trade-Off (ETTO) principle, which states there is a trade-off between efficiency or effectiveness on one hand, and thoroughness (such as safety assurance and human reliability) on the other hand”. (https://en.wikipedia.org/wiki/Efficiency%E2%80%93thoroughness_trade-off_principle).

 

In a biomedical laboratory, what are the goal conflicts and trade-offs, do the workers know that they are making trade-offs, and how do they ensure that they are making the right trade-offs? These are the questions we asked in a study we undertook. Time is the key goal conflict, especially when they are working on time-sensitive experiments or when they are at the end of a month-long experiment. Pressure to publish and to ensure good reproducible results, small sample quantities, and high cost of reagents pose further goal conflicts. The workers are aware of the tradeoffs and mentally calculate the risk at each step of the work. Safety professionals should understand and cater for these real-world situations, to achieve a holistic approach to safety.

 

ETTOing well is the pathway to glory; ETTOing badly will make you feel sorry

(Eric Hollnagel who described ETTO)


 

Confronting the Dual Use Dilemma and the International Network on Biotechnology

Dr. Irma R. Makalinao, MD, MA (Peace and Security Studies)

Professor 12 and Graduate Program Director

Department of Pharmacology and Toxicology

University of the Philippines College of Medicine

 

What is the dual-use dilemma? Dual use refers to materials, technologies and knowledge can that can be used for good and for harmful purposes.  Earlier, the term dual use has been associated with technology transfers between civilian and military applications. In the realm of WMD non-proliferation treaties and related laws integrates the concept of dual use for civilian (peaceful versus non-peaceful) and military purpose (benevolent and malevolent purpose) into a single conceptual framework.  The governance of dual use should consider both national security and human security.  Literature review shows that the new focus has shifted from national security issues related to potential military uses of dual-use technology to people-centered security concerns.  The Fink Report has specifically focused on engaging the life sciences in security through the development of communication channels between the life science community and security officials.  This presentation will provide an overview of the dual-use dilemma from the perspective of the Philippines in relation to the strategic trade management act, the CBRN National Action Plan and international obligations to the BTWC, CWC and the UNSCR 1540.  The dual-use dilemma may require prohibitions in the form of norm, ethical codes and laws.

 A brief discussion on the dual-use concept from lethality analysis perspective versus  intent will be included especially in dealing with dual-use science.

 The International Network on Biotechnology (INB)  is a global network committed to advancing education and raising-awareness about responsible life science. Focusing on emerging developments in the life sciences  and  biotechnology,  the  INB’s  work covers the subject areas of biosafety, biosecurity and bioethics The  INB  is administered  by the  United  Nations  Interregional  Crime  and  Justice Research Institute (UNICRI) and works closely with partner organizations engaged in complimentary missions (WHO, OIE, BWC-ISU, FBI, INTERPOL, and others). INB strives  to  make the  subject  of ‘responsible science’ more accessible and locally relevant.


 

Biosafety Level 3 Facility: Biosafety Versus Operation cost

Dr. Nguyen Thanh THUY 

Head, Department of Biosafety and Quality Management

National Institute of Hygience and Epidemiology

 

In the recent years, global epidemics are getting more and more complex. For the diagnosis or research of dangerous infectious pathogens, the bio containment facilities is needed. In 2008, with the support from Japanese International Cooperation Agency (JICA), a BSL3 facility including 4 laboratories were constructed at National Institute of Hygiene and Epidemiology (NIHE). These laboratories have been used for research and diagnosis of Influenza A/H5N1, Influenza A/H1N1, Anthrax, Rabies, Drug Resistant Tuberculosis, MERS CoV…

As the initial design, the BSL3 facility must be operated continuously 24 hours per day in all days of the years, except the maintenance time. The cost of energy consumption (including electricity and oil) is about 150,000 USD per year. This amount is a big challenges for NIHE. Since 2010, an initiative of "Developing energy saving operation mode for BSL3 laboratories" was developed and implemented. After 3 years of testing and evaluation, the solution was approved by the NIHE scientific committee. With energy saving operation mode, when no one working inside the laboratories, only one exhaust fan of biosafety cabinet is operated to maintain negative pressure (-50 Pa) inside laboratories meanwhile all HVAC system is turned off. Besides, issues related to the heat, humidity have been considered and addressed. The results showed that the operation cost of energy saving mode have been reduced by approximately 50% compared to initial mode; operation indicators such as air pressure, temperature, humidity also meet requirements; dust concentration meets requirements for clean room level 7 of ISO 14644-1. The annual risk assessment showed that the energy saving operation mode for BSL3 laboratories is acceptable, no increasing of biorisk at the BSL3 facility. So far, after 5 year of applying the energy saving operation mode for the facility, no biosafety incident or accident occurred.

Standby mode of operation should be considered for all BSL3 facilities. 


 

The ways forward for Biosafety and Biosecurity Program in Cambodia

Dr. SAU Sokunna

Deputy Director of DHS.MoH

Director of NMMLN

Director of National Biosafety Committee

 

Biosafety program has been growing in recent years in Cambodia. Biosafety guideline and biosafety curriculum were developed. The biosafety curriculum is focusing on biosafety and biorisk management for laboratory managers and biosafety officers to better control risk associated with biological material. The majority of the national biosafety committee has implemented accurate process for the quality standard which have potential to comply with IHR core capacity biosafety and biosecurity protocols, especially operating procedures related to concepts and skills to develop a sustainable education and awareness system and the training contents related to biosafety /biosecurity/biorisk management.


 

Biosafety practice and training in Western Africa during the 2014-2016 Ebola epidemic: supports from China CDC

Prof. William J. Liu

Associate Professor

National Institute for Viral Disease Control and Prevention, China CDC

 

During the 2014-2016 Ebola epidemic, hundreds of Chinese health care workers including physicians for Ebola virus infection treatment, epidemiologists for the public health training, and the Ebola test teams were sent to the West Africa. The Sierra Leone-China Biological Safety Laboratory was newly established in Jui, Freetown, which is the first and state-of-the-art fixed BSL III Lab in West Africa. Since the establishment of the Laboratory on 11th February 2015, the major two tasks of the lab are 1) Ebola virus tests. 2) Human resource training. For the first function, over 14,000 specimens have been tested in the lab during the Ebola epidemic. The service of the lab covered 10 different districts of the country, in comprise of over half of the population of Sierra Leone. In the meantime, the lab collaborated with Ministry of Health and Sanitation, World Health Organization, and  US CDC in the virus persistence study project which provides important reference for the Ebola survivor management. Nearly 5,000 body fluid specimens from Ebola survivors have been tested in the lab. For the second important task, Sierra Leone-China Biological Safety Laboratory plays a pivotal role in the training of the laboratory workforce for the country. Dozens of local laboratory specialists been well trained in the lab on the virus test and biological safety, who have later been the major force for the Ebola diagnosis and surveillance in different organizations of the country. The MOHS of Sierra Leone authorized the designation of the laboratory as the “National Reference Laboratory for Viral Hemorrhagic Fevers” and the “National Training Center for Virus Detection and Biosafety” in the end of June, 2016. China CDC will strengthen the support of the research on and pre-warning of tropical diseases in West Africa. 


Laboratory Biorisk and Beyond – Challenges of Developing Countries

Dr. Darouny PHONEKEO

Deputy Director

Institut Pasteur du Laos

 

Despite of various emerging and re-emerging diseases occurred in developing countries, the implementation of Biosafety/Biosecurity program in these countries, including Laos continue to be a big challenging. To face this critical situation, the Lao government, with help of international organizations has developed a regulatory framework and guidelines for biorisk management. Several Biosafety and Biosecurity trainings have been conducted to all central and provincial laboratories. However, they remain limited for the district health Center levels. Still the majority of Laboratories do not have proper biological waste management program. Hence, this is a big challenge in the Health sector, long term plan with multi-sectorial partnerships should be initiated.


 

NSF Accreditation of Biosafety Cabinet Field Certifiers

Ms. Maren Roush

Program Manager, Biosafety Cabinetry Certification

NSF International

 

NSF offers two personnel accreditation programs that evaluate the proficiency of individuals who perform field certification of biosafety cabinets (BSCs): an enhanced accreditation program for BSC field certifiers in North America and a basic accreditation program for BSC field certifiers outside of North America. These programs include written (theoretical) and practical (hands-on) examinations, along with continuing education and ethics requirements.

NSF's enhanced accreditation program is recognized as the premier credential in North America for individuals who certify Class II BSCs in hospitals, laboratories and research facilities. Until 2017, this program was NSF's only accreditation option for all BSC field certifiers worldwide.

In response to a demonstrated need for improved global field certification infrastructure and at the request of various stakeholder groups, NSF initiated the basic accreditation program in 2017. The basic accreditation program is intended to be more accessible to field certifiers who live and work in targeted areas outside of North America, both in terms of overall cost and availability of testing options in country. The basic accreditation program includes many of the same components as the enhanced program, but is tailored to the international marketplace. It is intended to provide trained field certifiers with credentials to show prospective clients and promote general awareness of the need for routine BSC maintenance. Additional focus is given to international standards other than NSF/ANSI 49 and test methodologies that utilize accessible equipment.

This presentation will provide information about the components of NSF’s basic accreditation program for BSC field certifiers, in addition to a review of the drivers that led to its creation, program goals, and anticipated long-term public health benefits.


 

 

 

 

 

 

Hotel Accommodation

 

Lotte Hotel Legend Saigon
2A-4A Tôn Đức Thắng,
Bến Nghé, Quận 1,
Hồ Chí Minh
Vietnam

 

Accommodation & Room Reservation:

 

Download room reservation form HERE to enjoy special room rate for conference delegates 

Sponsorship & Exhibition Opportunity

 

2 days of exhibition booth space on conference days (24 - 25 August 2017)

Advertisement space in the program booklet, sponsorship of luncheon, coffee break and many more options to fit your expectation.

  • Download the Sponsorship Prospectus HERE
  • Download the Sponsorship Application Form HERE
  • Please see exhibition booth floor plan HERE  to choose your ideal booth

IFBA Certification Exam

 

The IFBA is pleased to collaborate with the A-PBA in the delivery of the IFBA’s Professional Certifications during their upcoming12th Biosafety Conference. The exam session will be held at 2pm on August 23rd in Ho Chi Minh City, Vietnam. For further details on the event click here.

 

In addition to offering the Professional Certification in Biorisk Management, we will also be offering the new IFBA Professional Certifications in Biosecurity, Biocontainment Facilities, Biosafety Cabinets and Biological Waste Management. Only those individuals who have successfully completed the pre-requisite Biorisk Management certification are eligible for these new certifications. For information on the exam content, study materials and sample questions, click here

 

All applications must be processed through the on-line Certifior system at https://ifba.certifior.com. These instructions will guide individuals through the application process. For further details and enquiries on this session please contact the IFBA Secretariat by email at secretariat@internationalbiosafety.org.

Enquiry & Contact

 

General Enquiry for Registration and Payment for conference, workshop, & Booth Exhibition etc:

 

Accommodation & Room Reservation:

 

Exhibition Booth Logistic Matter:

 

Other Inquiry:

Please scan copy of your passport and email to Ms. Chi Mai from NIHE (email: ndcm@nihe.org.vn) for assistance       
  • Scan copy  of your passport.
  • A-PBA registration /invitation letter
  • Flight /accommodation itinerary (arrival and departure date etc)
Please scan the following documents and email to Ms. Chi Mai from NIHE (email: ndcm@nihe.org.vn) for assistance.

 

  • Scan copy  of your passport.
  • A-PBA registration /invitation letter
  • Flight /accommodation itinerary (arrival and departure date etc)

A-PBA Annual General Meeting (AGM) 2017 

 

This is to announce that A-PBA Annual General Meeting (AGM) 2017 will be held in conjunction with the A-PBA 12th Biosafety Conference in Ho Chi Minh, Vietnam:

 

Date     : 24  Aug 2017
Venue  : Lotte Legend Hotel Saigon - Ho Chi Minh City, Vietnam
Time    : 5.00pm local time 

 

Proposed Agenda of AGM:

 

  1. Adoption of the minutes of AGM 2016
  2. Annual report from A-PBA EXCO April 2016 - April 2017
  3. Presentation of Financial Year (FY) 2016 Report
  4. Motion from EXCO  
    • Nomination of 5 Executive Council Committee Members
    • Extension of nomination / voting exercise at the AGM
  5. Members’ motions
  6. Other matter & updates

 

A special members’ motion may be requested (by no less than 7 voting members) to be included in the agenda of the AGM, by writing to the Secretary no later than 10  Aug 2017.

 

Note: Only active voting members (non-expiring individual membership) are allowed to vote at the AGM.